产品货号：
Z29949
中文名称：
VPS24抗体
英文名称：
Anti-VPS24 Antibody (N-term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-VPS24 Antibody (N-term) |
| 指标别名 | CGI 149;CHMP3;Chromatin modifying protein 3;hVps24;NEDF;VPS24 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB |
| 基因名称 | CHMP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This CHMP3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-61 amino acids from the N-terminal region of human CHMP3. |
| 计算分子量 | 25kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins,such as stimulated growth factor receptors,lysosomal enzymes and lipids.The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and -III complexes.ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.The ESCRT machinery also functions in topologically equivalent membrane fission events,such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities,possibly in conjunction with the AAA ATPase VPS4.Selectively binds to phosphatidylinositol 3,5-bisphosphate PtdIns (3,5)P2 and PtdIns (3,4)P2 in preference to other phosphoinositides tested.Involved in late stages of cytokinesis.Plays a role in endosomal sorting/trafficking of EGF receptor.Isoform 2 prevents stress- mediated cell death and accumulation of reactive oxygen species when expressed in yeast cells. |
| Uniprot ID | Q9Y3E7 |
相关搜索：VPS24抗体，VPS24(N-term)多抗，Anti-VPS24 Antibody (N-term)